The study of culture redox potential’s effect on glycosylation and production of monoclonal antibodies in mammalian cell cultures
The glycosylation patterns of monoclonal antibodies (Mabs) have become very important in determining therapeutic abilities of many drugs. The thesis studied 3 cell lines producing humanized Mabs in the presence of variable concentrations of the reducing agent dithiothreitol (DTT) to artificially lo...
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2015
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| Online Access: | http://hdl.handle.net/1993/30224 |