Oxidative modification of vesicular transporters in an animal model of Alzheimer’s disease

Oxidative stress is one of the major characteristics in Alzheimer’s disease, and converging evidence indicates that cysteine S-nitrosylation might be related in AD pathology. My results demonstrated exogenous S-nitrosoglutathione was able to S-nitrosylate vAChT, vMAT2, vGluT1 and vGluT2. S-nitrosyla...

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Bibliographic Details
Main Author: Wang, Ying
Other Authors: Wang, Jun-Feng (Pharmacology & Therapeutics)
Published: 2015
Subjects:
Online Access:http://hdl.handle.net/1993/30316