The effect of SRA intron-1 splicing on differential ratio of SRA-SRAP levels and on ER-mediated transcription in breast cancer cells

The steroid receptor RNA activator gene (SRA1) generates two distinct entities. SRA RNA coactivates several NRs whereas SRA protein (SRAP) is suspected to regulate the activity of several transcription factors, including estrogen receptors (ER). Splicing of SRA intron-1 is the major event definin...

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Bibliographic Details
Main Author: Guo, Jimin
Other Authors: Leygue, Etienne (Biochemistry and Medical Genetics)
Language:en_US
Published: 2008
Subjects:
Online Access:http://hdl.handle.net/1993/3097