Investigation of Inducible Mitogen and Stress Activated Protein Kinase 1 (MSK1) and Histone H3 Phosphorylation by the RAS-MAPK Pathway in Cancer Cells

Investigation of Inducible Mitogen and Stress Activated Protein Kinase 1 (MSK1) and Histone H3 Phosphorylation by the RAS-MAPK Pathway in Cancer Cells

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The RAS-mitogen-activated protein kinase (MAPK) pathway is an essential signaling mechanism that regulates cellular processes and culminates in the activation of specific gene expression programs. Alterations in the RAS-MAPK signaling cascade can modify epigenetic programs and confer advantages in c...

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Bibliographic Details
Main Author: Espino, Paula
Other Authors: Davie, James (Biochemistry and Medical Genetics)
Language:en_US
Published: 2010
Subjects:
cell signaling
MSK1
H3 phosphorylation
chromatin
cancer
gene expression
Online Access:http://hdl.handle.net/1993/4148

Internet

http://hdl.handle.net/1993/4148

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