Beneficial effects of quetiapine in the APP/PS1 transgenic mice: implications for early intervention for Alzheimer's disease
Alzheimer's disease (AD) is the leading cause of dementia. Amyloid plaques in the brain remain a pathological feature of AD. These plaques are primarily composed of amyloid β-protein (Aβ). It has been postulated that glycogen synthase kinase-3β (GSK3β) activity might exert a central role in the...
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Language: | en_US |
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2011
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Online Access: | http://hdl.handle.net/1993/4736 |