Identification and characterization of BRN3A/BRN3B as DLX homeobox gene transcriptional targets in retinal development

Introduction: The Dlx1/Dlx2 double knockout mouse has reduced numbers (33% fewer) of retinal ganglion cells (RGC), due to enhanced apoptosis. Brn3a and Brn3b are closely related members of the Class IV POU-domain gene family, and play functionally interchangeable roles in retinal development. We hyp...

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Bibliographic Details
Main Author: Zhang, Qi
Other Authors: Eisenstat, David (Human Anatomy & Cell Science)
Published: 2011
Subjects:
Dlx
Online Access:http://hdl.handle.net/1993/4799