De Novo Sequence Assembly of Viral Quasispecies
The rapid replication and high mutation rates of viruses like HIV lead to the formation of a community of highly similar genomes, referred to as a viral quasispecies, in an infected individual. Next-generation sequencing technologies enable researchers to sequence a complete quasispecies community w...
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2012
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| Online Access: | http://hdl.handle.net/1993/9591 |