Modeling the flexibility of alpha helices in protein interfaces : structure based design and prediction of helix-mediated protein-protein interactions

Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2008. === Vita. === Includes bibliographical references. === Protein-protein interactions play an essential role in many biological functions. Prediction and design of these interactions using computational methods requires...

Full description

Bibliographic Details
Main Author: Apgar, James R. (James Reasoner)
Other Authors: Amy E. Keating.
Format: Others
Language:English
Published: Massachusetts Institute of Technology 2008
Subjects:
Online Access:http://hdl.handle.net/1721.1/43778