Low dose tolerance vaccine platform, reovirus protein sigma 1, and treatment of autoimmunity
Effective treatments for multiple sclerosis (MS) are problematic due to its unknown etiology. Experimental autoimmune encephalomyelitis (EAE) in rodents mimics MS. Mucosal treatment of EAE with antigens to induce tolerance is effective, but requires large and/or multiple administrations, which intro...
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| Language: | en |
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2008
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| Online Access: | http://etd.lib.montana.edu/etd/2008/rynda/RyndaA1208.pdf |