Using NMR spectroscopy to investigate the binding of DNA to the globular domain of histone H1.0

<p>Linker histones (H1) are a family of lysine-rich proteins that bind to or near the point at which DNA enters and exits the nucleosomal core. A number of studies have shown that H1 expression levels are altered in cancer and that variant-specific changes can be observed in different tumor ce...

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Bibliographic Details
Main Author: Tata, Sri Ramya
Other Authors: Dr. Nicholas C. Fitzkee
Format: Others
Language:en
Published: MSSTATE 2016
Subjects:
Online Access:http://sun.library.msstate.edu/ETD-db/theses/available/etd-03162016-124953/