The effect of molecular crowding on the stability of human c-MYC promoter sequence i-motif at neutral pH
<p>The oncogene c-MYC has guanine-rich and complementary cytosine-rich sequences in its P1 promoter region. The P1 promoter is responsible for over 90% of the c-MYC expression. Downregulation of c-MYC expression represents a novel therapeutic approach to more than 50% of all cancers. A stable...
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| Format: | Others |
| Language: | en |
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MSSTATE
2013
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| Online Access: | http://sun.library.msstate.edu/ETD-db/theses/available/etd-07022013-134846/ |