Establishing the structure function relationship of polypyridyl ruthenium and Berenil-type compounds in the formation of complexes with B-DNA and/or G-quadruplex DNA

<p>Cancer results from the accumulation of genetic mutations in a normal cell that ultimately result in the expression (or overexpression) of oncogenes. The design of drugs having high affinity for specific DNA sequences or structural motifs is vital to gaining a better understanding of gene e...

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Bibliographic Details
Main Author: Mikek, Clinton Gregory
Other Authors: Dongmao Zhang
Format: Others
Language:en
Published: MSSTATE 2017
Subjects:
Online Access:http://sun.library.msstate.edu/ETD-db/theses/available/etd-07212017-092534/