Understanding binding-induced conformational change in the Pin1 Prolyl Isomerase
<p>Pin1 is a Prolyl Isomerase that catalyzes cis-trans isomerization of peptides with pSer/Thr-Pro motifs in many cell signaling proteins. This conformational switch is implicated in diseases. Pin1 activity is considered a target for therapeutic applications. Pin1 targets motifs by its N-termi...
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Others |
| Language: | en |
| Published: |
MSSTATE
2013
|
| Subjects: | |
| Online Access: | http://sun.library.msstate.edu/ETD-db/theses/available/etd-10302013-204949/ |