Regulated intramembrane proteolysis of NRG1 type III dediates postnatal peripheral myelination
Neuregulin-1 (NRG1) type III is a growth factor on the surface of neurons in the peripheral nervous system (PNS). It is required for initial myelination of nerves by Schwann cells after birth and for remyelination after injury. Neuregulin-1 type III is activated by cleavage (shedding) in its extrace...
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Ludwig-Maximilians-Universität München
2015
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| Online Access: | http://edoc.ub.uni-muenchen.de/18372/1/Fleck_Daniel.pdf http://nbn-resolving.de/urn:nbn:de:bvb:19-183725 |