Targeted cancer therapy systems:: an in silico study of radiohalogenated ligands in the estrogen receptor and the synthesis of a molecular toolkit for the fabrication of customizable nanoparticles.

Chemotherapy is often limited by off-target toxicity and the development of multi-drug resistance in response to treatment. Strategies which reduce off-target toxicity by passively or actively targeting cancer cells may improve the efficacy of chemotherapy. Herein, two projects relating to targeted...

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Online Access:http://hdl.handle.net/2047/d20018709