EPR study of ligand-receptor interactions: measuring ligand induced changes in dynamics and structure of the estrogen receptor ligand binding domain.
Ligand-receptor interactions are powerful determinants of biochemical pathways. In this work, the role of ligand binding and coregulator interaction is examined in particular as it related to changes in receptor dynamics and conformation. The emerging technique of site directed spin labeling and ele...
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| Online Access: | http://hdl.handle.net/2047/d10016946 |