Flow-induced modulations of endothelial glycocalyx are potential gateways for circulating tumor cell extravasation
Background: One of the major events leading to cancer metastasis is extravasation - a process of circulating tumor cells (CTCs) exiting the blood stream across the endothelium and migrating into tissue at the secondary tumor site. Tethering, rolling and arrest of CTCs is mediated by the binding of t...
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| Online Access: | http://hdl.handle.net/2047/D20328712 |