Genetic engineering of Catharanthus roseus to enhance production of anticancer pharmaceutical compounds

The medicinal plant, Catharanthus roseus, is the source of pharmaceutically valuable anticancer alkaloids, vincristine (VCR) and vinblastine (VBL). These alkaloids are produced only in C. roseus and at extremely low levels (0.0002 wt%). Due to their low levels, the isolation of these compounds is bo...

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Online Access:http://hdl.handle.net/2047/D20194128