Effect of various parameters on in vivo Aflatoxin B₁ binding to rainbow trout (Salmo gairdneri) liver DNA

Aflatoxin B₁ (AFB₁,) is a potent liver carcinogen to a number of animal species including rainbow trout (Salmo gairdneri). Microsomal activation is required for the in vitro conversion of AFB, to a reactive metabolite, thought to be the AFB₁,-2,3-oxide, which will bind nucleic acids, produce toxicit...

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Bibliographic Details
Main Author: Whitham, Mark
Other Authors: Nixon, J. E.
Language:en_US
Published: 2012
Subjects:
Online Access:http://hdl.handle.net/1957/27487