Effect of various parameters on in vivo Aflatoxin B₁ binding to rainbow trout (Salmo gairdneri) liver DNA
Aflatoxin B₁ (AFB₁,) is a potent liver carcinogen to a number of animal species including rainbow trout (Salmo gairdneri). Microsomal activation is required for the in vitro conversion of AFB, to a reactive metabolite, thought to be the AFB₁,-2,3-oxide, which will bind nucleic acids, produce toxicit...
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Language: | en_US |
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2012
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Online Access: | http://hdl.handle.net/1957/27487 |