1) Preparation of acetaminophen capsules containing beads prepared by hot-melt direct blend coating method 2) Pharmacokinetic modeling and Monte Carlo simulations in context of additional criteria for bioequivalence assessments 3) Pharmacokinetic prediction of levofloxacin accumulation in tissue and its association to tendinopathy
The thrust of this thesis is to study oral solid dosage formulation using hot melt coating method and to use pharmacokinetic modeling and simulation (PK M&S) as a tool that can help to predict pharmacokinetics of a drug in human and the probability of passing various bioequivalence criteria of t...
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| Language: | en_US |
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2012
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| Online Access: | http://hdl.handle.net/1957/29715 |