Clinical pharmacokinetic simulation/modeling as a tool for therapeutic drug monitoring and dose adjustment in special patient populations

This dissertation describes how to apply pharmacokinetic simulations and modeling in a clinical setting to monitor and adjust drug dosing in special patient populations. Pharmacokinetic simulations were used to investigate efficacy and risk of drug toxicity of a new dosing regimen for aminoglycoside...

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Bibliographic Details
Main Author: Mohamed, Osama H.
Other Authors: Ayres, James W.
Language:en_US
Published: 2012
Subjects:
Online Access:http://hdl.handle.net/1957/29720