Control of muscle protein degradation and steady-state poly(ADP-ribose) polymerase concentration by calpain
The first goal of this study was to understand the role of calpains in skeletal muscle protein degradation in cultured cells. We have developed a genetic approach to inhibit endogenous calpain activity through over-expressing dominant negative m-calpain (DN), antisense m-calpain (AS) and calpastatin...
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| Language: | en_US |
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2012
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| Online Access: | http://hdl.handle.net/1957/33998 |