The Role of the Wiskott-Aldrich Syndrome Protein in Regulating T Cell Programmed Cell Death Mechanisms and Implications for Autoimmunity in the Wiskott-Aldrich Syndrome

<p> The development of autoimmunity in the setting of immunodeficiency has been a paradoxical observation. Many primary immunodeficiency diseases (PIDDs) are associated with autoimmunity. Wiskott-Aldrich Syndrome (WAS), a PIDD caused by defects in the Wiskott-Aldrich Syndrome protein (WASp),...

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Bibliographic Details
Main Author: Marjanovic, Sophia Y.
Language:EN
Published: The George Washington University 2016
Subjects:
Online Access:http://pqdtopen.proquest.com/#viewpdf?dispub=10006518