Identification of drug sensitive gene motifs using "epigenetic profiles" derived from bioinformatics databases
<p> The use of epigenetic modifying drugs such as DNA methyltransferase inhibitors (DNMTi) and histone deacetylase inhibitors (HDACi) is becoming more common in the treatment of cancer. Currently, there is a profound interest in determining predictive biomarkers for patient response and the ef...
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| Language: | EN |
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The University of North Carolina at Greensboro
2016
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| Online Access: | http://pqdtopen.proquest.com/#viewpdf?dispub=10123750 |