Design of novel chimeras provides insight into structure/function activity of apolipoprotein E3 and apolipoprotein AI
<p> Apolipoprotein (apo) E3 (299 residues, ∼34 kDa) and apoAI (243 residues, ∼28 kDa) are exchangeable apolipoproteins that play a dominant role in regulating plasma cholesterol levels and are considered anti-atherogenic. The N-terminal (NT) domain of apoE3 mediates cellular up...
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Language: | EN |
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California State University, Long Beach
2017
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Online Access: | http://pqdtopen.proquest.com/#viewpdf?dispub=10196288 |