Design of novel chimeras provides insight into structure/function activity of apolipoprotein E3 and apolipoprotein AI

Design of novel chimeras provides insight into structure/function activity of apolipoprotein E3 and apolipoprotein AI

<p> Apolipoprotein (apo) E3 (299 residues, &sim;34 kDa) and apoAI (243 residues, &sim;28 kDa) are exchangeable apolipoproteins that play a dominant role in regulating plasma cholesterol levels and are considered anti-atherogenic. The N-terminal (NT) domain of apoE3 mediates cellular up...

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Bibliographic Details
Main Author:	Lek, Mark T.
Language:	EN
Published:	California State University, Long Beach 2017
Subjects:	Biochemistry
Online Access:	http://pqdtopen.proquest.com/#viewpdf?dispub=10196288

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