Characterization of ubiquitin-proteasome dynamics in Caenorhabditis elegans muscle cells during protein-folding stress

<p> In order to adapt to changing conditions and life stages, cells must remodel the composition of the proteome by specifically removing obsolete or damaged proteins. Failure to remove proteins at the appropriate time can cause a variety of cellular dysfunctions that can lead to cell death an...

Full description

Bibliographic Details
Main Author: Skibinski, Gregory A.
Language:EN
Published: The University of Alabama in Huntsville 2017
Subjects:
Online Access:http://pqdtopen.proquest.com/#viewpdf?dispub=10248862