A Characterization of MK-STYX, A Catalytically Inactive Phosphatase Regulating Mitochondrial Apoptosis

<p> Chemoresistance is a highly significant problem affecting a diverse array of cancers at all clinical stages. In an attempt to identify molecular mechanisms leading to chemoresistance, we performed a RNAi screen against all known and putative kinases and phosphatases in the human genome. Th...

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Bibliographic Details
Main Author: Niemi, Natalie Marie
Language:EN
Published: Van Andel Research Institute 2017
Subjects:
Online Access:http://pqdtopen.proquest.com/#viewpdf?dispub=10274627