Investigating the Use of TGF-beta2 to Downregulate MHC Expression and Reduce the Immunogenicity of Equine Bone Marrow-derived Mesenchymal Stem Cells
<p> Allogeneic bone marrow-derived mesenchymal stem cells (MSCs) are a promising cell therapy for effective and efficient treatment of various inflammatory and immunemediated diseases. While the prevailing dogma has been that MSCs are immune privileged, very few studies have controlled for MHC...
Main Author: | |
---|---|
Language: | EN |
Published: |
North Carolina State University
2018
|
Subjects: | |
Online Access: | http://pqdtopen.proquest.com/#viewpdf?dispub=10970022 |