Investigating the Use of TGF-beta2 to Downregulate MHC Expression and Reduce the Immunogenicity of Equine Bone Marrow-derived Mesenchymal Stem Cells

<p> Allogeneic bone marrow-derived mesenchymal stem cells (MSCs) are a promising cell therapy for effective and efficient treatment of various inflammatory and immunemediated diseases. While the prevailing dogma has been that MSCs are immune privileged, very few studies have controlled for MHC...

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Bibliographic Details
Main Author: Berglund, Alix Kay
Language:EN
Published: North Carolina State University 2018
Subjects:
Online Access:http://pqdtopen.proquest.com/#viewpdf?dispub=10970022