On the Structure-Property Relationships of Oligonucleotide Polyelectrolyte Complexes and Complex Micelles

<p> Oligonucleotides, short nucleic acids of &ap; 100 bases and under, are therapeutics of great interest because of their ability to regulate gene expression and improve outcomes in diseases like cancer and atherosclerosis. However, they are vulnerable to degradation by enzymes in the bod...

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Bibliographic Details
Main Author: Lueckheide, Michael James
Language:EN
Published: The University of Chicago 2019
Subjects:
Online Access:http://pqdtopen.proquest.com/#viewpdf?dispub=10978422