The Effect of Biglycan on TNF-alpha Signaling and Innervation in the Intervertebral Disc

<p> Biglycan is a small, leucine-rich repeat proteoglycan that has been shown to be elevated in the intervertebral discs (IVDs) of older adults (Cs-Szabo, 2002) and can interact with many different signaling molecules and structural proteins. TNF-alpha (TNF) is a general modulator of inflammat...

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Bibliographic Details
Main Author: Buchanan, Samuel Andrew
Language:EN
Published: Rush University 2016
Subjects:
Online Access:http://pqdtopen.proquest.com/#viewpdf?dispub=1581897