Constitutively Decreased Transforming Growth Factor Beta Receptor 1 (TGFBR1) Signaling Modifies Colorectal Cancer Predisposition

<p> Colorectal cancer (CRC) is the third most commonly diagnosed cancer and the third leading cause of cancer death in the United States. Twin cohort studies indicate that inherited susceptibility accounts for approximately 35% of all CRC cases, but only 5-6% of CRC cases can be attributed to...

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Bibliographic Details
Main Author: Pennison, Michael James
Language:EN
Published: Northwestern University 2015
Subjects:
Online Access:http://pqdtopen.proquest.com/#viewpdf?dispub=3741319