Redundancy-aware learning of protein structure-function relationships

The protein kinases are a large family of enzymes that play a fundamental role in propagating signals within the cell. Because of the high degree of binding site similarity shared among protein kinases, designing drug compounds with high specificity among the kinases has proven difficult. However,...

Full description

Bibliographic Details
Main Author: Bryant, Drew
Other Authors: Kavraki, Lydia E.
Format: Others
Language:English
Published: 2013
Subjects:
Online Access:http://hdl.handle.net/1911/71132