Integration of SHH and WNT pathways controls morphogenesis of the CNS.
Dorsoventral patterning of the vertebrate nervous system is achieved by the combined activity of morphogenetic signals secreted from dorsal and ventral signalling centres. The Shh/Gli pathway plays a major role in patterning the ventral neural tube; however, the molecular mechanisms that limit targe...
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| Format: | Doctoral Thesis |
| Language: | Catalan |
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Universitat de Barcelona
2008
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| Online Access: | http://hdl.handle.net/10803/1894 http://nbn-resolving.de/urn:isbn:9788469153659 |