Force-spectroscopy of small ligands binding to nucleic acids
Single-molecule techniques allow to following biomolecular reactions with unprecedented resolution. Particularly, optical tweezers can be used to manipulate and apply forces to individual molecules tethered between plastic beads that are optically-trapped. Optical trapping is achieved by using highl...
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| Format: | Doctoral Thesis |
| Language: | English |
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Universitat de Barcelona
2015
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| Online Access: | http://hdl.handle.net/10803/286597 |