Pharmacological blockade of voltage-gated calcium channels as a potential cardioprotective strategy
Voltage-gated Ca2+ channels (VGCCs) are essential for initiating and regulating cardiac function. During the cardiac action potential, Ca2+ influx through L-type channels triggers the sarcoplasmic reticulum Ca2+ release that enables the EC coupling. Ca2+ can also enter cardiac myocytes through low-v...
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| Format: | Doctoral Thesis |
| Language: | English |
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Universitat de Lleida
2014
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| Online Access: | http://hdl.handle.net/10803/285047 |