A contribution of budding yeast to unravel aging. Entry into quiescence relies on the transceptor Mtl1 by sensing nutrients and regulation of signaling pathways
Saccharomyces cerevisiae is a premier model system to study ageing in post mitotic cells. In this study, we show that Mtl1, member of the Cell Wall Integrity pathway (CWI), plays a positive role in Chronological Life Span (CLS). The absence of Mtl1 shortens CLS whereas its overexpression extends it....
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| Format: | Doctoral Thesis |
| Language: | English |
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Universitat de Lleida
2015
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| Online Access: | http://hdl.handle.net/10803/286033 |