Allosteric interactions at the M3 muscarinic acetylcholine receptor
The extracellular loops of muscarinic acetylcholine receptors are predicted to play a role in the binding and regulation of allosteric modulators. Furthermore, the sequence of the five subtypes of muscarinic receptors shows a large degree of diversity in this region. M3 receptor mutants, K523E, D518...
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Doctoral Thesis |
| Language: | English |
| Published: |
Universitat Politècnica de Catalunya
2008
|
| Subjects: | |
| Online Access: | http://hdl.handle.net/10803/6469 http://nbn-resolving.de/urn:isbn:9788469199954 |