Role of EphB receptors in intestinal epithelial cell positioning and colorectal cancer progression

In the intestinal epithelium, Wnt signaling drives the expression of the genes encoding tyrosine kinase receptors EphB2 and EphB3 and represses the expression of their membrane-tethered ligands, ephrin-Bs. Eph-ephrin interactions result in cellular repulsion and are involved in boundary formation. T...

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Bibliographic Details
Main Author: Cortina Duran, Carme
Other Authors: Batlle Gómez, Eduard
Format: Doctoral Thesis
Language:English
Published: Universitat Pompeu Fabra 2009
Subjects:
57
Online Access:http://hdl.handle.net/10803/35692
http://nbn-resolving.de/urn:isbn: 978-84-694-9975-7