Role of EphB receptors in intestinal epithelial cell positioning and colorectal cancer progression
In the intestinal epithelium, Wnt signaling drives the expression of the genes encoding tyrosine kinase receptors EphB2 and EphB3 and represses the expression of their membrane-tethered ligands, ephrin-Bs. Eph-ephrin interactions result in cellular repulsion and are involved in boundary formation. T...
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Format: | Doctoral Thesis |
Language: | English |
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Universitat Pompeu Fabra
2009
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Online Access: | http://hdl.handle.net/10803/35692 http://nbn-resolving.de/urn:isbn: 978-84-694-9975-7 |