Regulation of NFAT5 by signaling pathways involved in osmotic stress responses and cell growth
NFAT5 is the main regulator of an osmoprotective gene program that is switched on by osmotic stress. Hypertonicity causes a harmful increase in the intracellular concentration of inorganic ions and NFAT5-regulated genes allow the accumulation of organic osmolytes and chaperones in order to protect t...
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| Format: | Doctoral Thesis |
| Language: | English |
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Universitat Pompeu Fabra
2008
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| Online Access: | http://hdl.handle.net/10803/77906 |