Generation of human dopaminergic neurons from induced pluripotent stem cells to model Parkinson's disease

Generation of human dopaminergic neurons from induced pluripotent stem cells to model Parkinson's disease

Parkinson’s disease (PD) is an incurable, chronically progressive neurodegenerative disease leading to premature invalidity and death. The locomotor disability of PD patients is mainly rooted in the gradual and insidious degeneration of dopaminergic neurons (DA) projecting from the midbrain substant...

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Bibliographic Details
Main Author: Sánchez Danés, Adriana, 1984-
Other Authors: Consiglio, Antonella
Format: Doctoral Thesis
Language:English
Published: Universitat Pompeu Fabra 2012
Subjects:
Pluripotent stem cells
Parkinson’s Disease
Dopaminergic neurons
LMX1A
Disease modeling
Neurodegeneration
Cèl•lules mare pluripotents
Malaltia de Parkinson
Neurones dopaminèrgiques
Modelatge de malalties
Neurodegeneració
616.8
Online Access:http://hdl.handle.net/10803/96912

Internet

http://hdl.handle.net/10803/96912

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