Generation of human dopaminergic neurons from induced pluripotent stem cells to model Parkinson's disease
Parkinson’s disease (PD) is an incurable, chronically progressive neurodegenerative disease leading to premature invalidity and death. The locomotor disability of PD patients is mainly rooted in the gradual and insidious degeneration of dopaminergic neurons (DA) projecting from the midbrain substant...
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Format: | Doctoral Thesis |
Language: | English |
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Universitat Pompeu Fabra
2012
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Online Access: | http://hdl.handle.net/10803/96912 |