THE PREPARATION AND CHARACTERIZATION OF PRO-APOPTOTIC PEPTIDE ALA-VAL-PRO-ILE AND ITS DERIVATIVES

Bioengineering === M.S. === The tetra-peptide sequence alanine-valine-proline-isoleucine (AVPI) is derived from a known inhibitor of apoptosis inhibitor proteins (IAPs) called Smac (second mitochondria-derived activator of caspases). Ala-Val-Pro-Ile can be further utilized as an anti-cancer agent by...

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Bibliographic Details
Main Author: Fang, Shinong
Other Authors: Suh, Won;
Format: Dissertation
Language:English
Published: Temple University Libraries 2018
Subjects:
Online Access:http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/490963