The Role of Ligand Induced Stabilization in the Allosteric Mechanism of Tetracycline Repressor
Allosteric regulation of proteins by reversible ligand binding is essential for regulation of fundamental biological processes. The mechanism by which a binding event alters the function of a distant site in a protein is only poorly understood. In this thesis, I use the Tetracycline Repressor (TetR)...
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Format: | Others |
Language: | en_ca |
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2008
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Online Access: | http://hdl.handle.net/1807/17242 |