The Role of Ligand Induced Stabilization in the Allosteric Mechanism of Tetracycline Repressor

Allosteric regulation of proteins by reversible ligand binding is essential for regulation of fundamental biological processes. The mechanism by which a binding event alters the function of a distant site in a protein is only poorly understood. In this thesis, I use the Tetracycline Repressor (TetR)...

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Bibliographic Details
Main Author: Reichheld, Sean
Other Authors: Davidson, Alan R.
Format: Others
Language:en_ca
Published: 2008
Subjects:
Online Access:http://hdl.handle.net/1807/17242