Synthesis of Fluorine-18 Labelled Radiotracers for Positron Emission Tomography
This work improved the radiosynthesis of a known M2 muscarinic receptor imaging agent, [18F]FP-TZTP, and subsequent syntheses and in vitro evaluation of several novel TZTP derivatives highlighted a lead compound which exhibited M4 potency and selectivity, the thioether fluoro-polyethyleneglycol, whi...
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| Language: | en_ca |
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2009
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| Online Access: | http://hdl.handle.net/1807/17719 |