Effective Neutrophil Activation During Innate Immunity: Understanding the Specific Roles of Rac1 and Rac2
Neutrophils migrate rapidly towards a site of inflammation and mediate bacterial killing through highly regulated pathways that involve the phagocytosis of bacteria and the generation of reactive oxygen species by the NADPH oxidase complex. The Rac small GTPases have prominent roles in the regulatio...
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| Language: | en_ca |
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2009
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| Online Access: | http://hdl.handle.net/1807/17798 |