The Role of CCL5/CCR5 Signal Transduction in T cell Function and Breast Cancer
Chemokines are responsible for directing leukocyte migration and triggering firm arrest by activating integrins on leukocytes. It is now apparent that chemokines have critical biological roles beyond chemo-attraction. Throughout this thesis, I describe the importance of the CCL5/CCR5 axis in the c...
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| Language: | en_ca |
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2009
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| Online Access: | http://hdl.handle.net/1807/17805 |