The Effect of Glucagon-like Peptide-2 on Insulin-like Growth Factor-1 in Murine Intestinal Subepithelial Myofibroblasts

The Effect of Glucagon-like Peptide-2 on Insulin-like Growth Factor-1 in Murine Intestinal Subepithelial Myofibroblasts

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Insulin-like growth factor-1 (IGF-1), a known secretory product of intestinal subepithelial myofibroblasts (ISEMF), is essential for the intestinotrophic effects of glucagon-like peptide-2(GLP-2). I hypothesized that GLP-2 increases the production of IGF-1 by primary murine ISEMF in culture. Immunoc...

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Bibliographic Details
Main Author: Leen, Jason
Other Authors: Brubaker, Patricia
Language:en_ca
Published: 2009
Subjects:
Cell cultures
Glucagon-like peptide-2
Subepithelial myofibroblasts
Insulin-like growth factor-1
PI3K/AKT signaling
Intestinal growth
Real time RT-PCR
Western blots
Immunocytochemistry
RIA
0719
Online Access:http://hdl.handle.net/1807/18828

Internet

http://hdl.handle.net/1807/18828

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