Novel Regulatory Mechanisms Underlying the Expression of the Carbohydrate Response Element Binding Protein (ChREBP): the Roles of Insulin and the POU Protein Oct-1
ChREBP has emerged as one of the key controllers of hepatic lipogenesis. While the function of ChREBP has been extensively investigated, mechanisms underlying its transcriptional regulation remain largely unknown. We located a conserved POU-binding site within mammalian ChREBP promoters, and demonst...
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| Language: | en_ca |
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2009
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| Online Access: | http://hdl.handle.net/1807/18859 |