Functional Analysis of the Thiol Oxidoreductase ERp57 and its Role in the Biogenesis of MHC Class I Molecules
Class I major histocompatibility complex molecules present antigenic peptides to cytotoxic T lymphocytes, which leads to the elimination of virus infected cells. Class I molecules are heterotrimers consisting of a heavy chain, a light chain termed beta2-microglobulin, and a peptide ligand. Assembly...
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| Language: | en_ca |
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2009
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| Online Access: | http://hdl.handle.net/1807/19120 |